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The mission of C3 is to leverage the collaborative opportunities offered by the existence of one of the only 46 NCI-designated comprehensive cancer centers (UC San Diego Moores Cancer Center) and two of the only 7 NCI-designated basic research cancer centers (Salk Institute for Biological Studies and Sanford Burnham Prebys Medical Discovery Institute) in the same city;

Consistent with this mission, C3's primary function is to provide an ongoing forum for advancing  cancer prevention and control, screening and therapy vis enhancing the interactions and collaborations among the three NCI-designated Cancer Centers in San Diego, as well as promoting interactions with other public and private sector organizations in San Diego.

Center Directors’ statements

Nov. 11 & 12, 2017
Petco Park 




C3 cores2.jpg




Full Application here: RFA

PURPOSE:  Proceeds from the November 2017 Padres Pedal the Cause are available to faculty members of the Salk, Moores, and Sanford Burnham Prebys (SBP) Cancer Centers (San Diego NCI Cancer Centers Council or C3), Rady Children's Hospital, and C3 members from UC San Diego-affiliated institutions (SDSU, JCVI, LJI, SIO) to stimulate scientific collaboration, team science, and innovativetranslational research related to the prevention, diagnosis, or treatment of cancer. Where relevant, proposed research projects should describe use of the C3 Shared Resources found on the C3 website ( Priority will be given to proposals that have a high likelihood of leading to extramural research funding, provide new approaches to important clinical or population/community challenges, or offer a clear route to a clinical trial.

·   Proposals led by Moores Cancer Center (MCC) population science faculty in collaboration with Salk and/or SBP faculty are highly encouraged and will be reviewed by investigators with appropriate expertise and weighed more heavily if it is particularly meritorious.
·   A separate, concurrent Rady Children's Hospital Translational Research Award is available to support faculty members and fellows in the UC San Diego Division of Hematology/Oncology and Department of Pediatrics towards research related to Pediatric Oncology. See separate Rady RFA.

NEW THIS YEAR! At least five (5) awards up to $125K for one (1) year are expected to be funded in 2018. 

1.    A Co-PI may submit only one (1) Pilot Grant application.
2.    Pilot Grant budget allocation for each C3 institution or Rady Children's must not be less than 30%.  
3.    REQUIRED to be a participant in the next Padres Pedal the Cause as a rider, volunteer, or virtual rider.

APPLICATION GUIDELINES: The deadline is 5:00 PM PST, FRIDAY, MARCH 2, 2018. The earliest starting date is JUNE 1, 2018. All applications (pdf) must be submitted electronically via the MCC web-based pilot project review system called WebGAAS: an application has been submitted electronically via WebGAAS, it cannot be changed.

BUDGETARY GUIDELINES:The budget may include partial salary support for faculty investigators, trainee investigators (graduate students/postdocs), laboratory technicians, and other related study expenses. Travel, professional meeting fees, salary support for administrative personnel, and equipment are excluded.
INQUIRIES:  Leona Flores, PhD, Padres Pedal/C3 Grant Scientific Administrator     
Email:; Phone: 858 / 822-0182     


2017 C3 / Padres Pedal the Cause
Pilot Grant Awardees
Project 1: “Oncogenic Regulation of B-Lymphomagenesis by the Chromatin Modulator DOT1L”
Bing Ren, PhD (Moores Cancer Center at UC San Diego Health)
Aniruddha Deshpande, PhD (Sanford Burnham Prebys Cancer Center)
Project 2: “Decoding Colon Cancers Using Boolean Principles”
Pradipta Ghosh, MD (Moores Cancer Center at UC San Diego Health)
Debashis Sahoo, PhD (Moores Cancer Center at UC San Diego Health)
Manuel Perucho, PhD (Sanford Burnham Prebys Cancer Center)
Project 3: “An over-expressed GPCR in pancreatic cancer associated fibroblasts as a novel therapeutic target”
Paul Insel, MD (Moores Cancer Center at UC San Diego Health)
Kristina Vuori, MD, PhD (Sanford Burnham Prebys Cancer Center)
Project 4: “Identification of genes critical for the production of T-cellss from human pluripotent stem cells for development of “off-the-shelf” T-cells immunotherapies”
Dan S. Kaufman, MD, PhD (Moores Cancer Center at UC San Diego Health)
Sumit K. Chanda, PhD (Sanford Burnham Prebys Cancer Center)
Project 5: “Irreversible electroporation as an In Situ vaccine for pancreatic cancer”
Rebekah White, MD (Moores Cancer Center at UC San Diego Health)
Steven Schoenberger, PhD (La Jolla Institute)
Project 6: “Targeting cellular mechanotransduction in breast cancer metastasis”
Jing Yang, PhD (Moores Cancer Center at UC San Diego Health)
Elena Pasquale, PhD (Sanford Burnham Prebys Cancer Center)